1762 - 1764: Montresor's Tramway, "the new railway replaced manual labor performed by the Seneca and touched off what might be the first labor rebellion in North America when the Seneca became unemployed"
1776: Watt steam engine.
1810 - 1828: Leiper Railroad.
1823: Delaware and Hudson Canal Company.
1825: Granite Railway.
1826: Mohawk & Hudson Railroad.
1830: Baltimore and Ohio Railroad. First common carrier.
1843: Congress appropriated $30,000 for construction of an experimental 38-mile (61 km) telegraph line between Washington, D.C., and Baltimore along the B&O's right-of-way.
1848: Houston and Texas Central Railway.
1848: Chicago, Burlington and Quincy Railroad.
Land Grant Act of 1850.
1853 - 1855: Pacific Railroad Surveys.
1861: First transcontinental telegraph.
1862: Pacific Railroad Acts.
1862: Central Pacific Railroad.
1862: Union Pacific Railroad.
1863: First transcontinental railroad.
1863: Brotherhood of Locomotive Engineers and Trainmen.
1868: Order of Railway Conductors.
1873: Brotherhood of Locomotive Firemen and Enginemen.
Great Railroad Strike of 1877.
1883: Brotherhood of Railroad Trainmen.
1883: Time Zones.
Great Southwest railroad strike of 1886.
1887: Brotherhood of Maintenance of Way Employees.
Interstate Commerce Act of 1887.
1887 - 1996: Interstate Commerce Commission.
- Burlington railroad strike of 1888.
1889: President Benjamin Harrison communicated to the United States Congress the concerns he possessed over the safety of railroad workers and the number of railroad work injuries that were happening. He even compared railroad work to war in terms of how dangerous the work was. U.S. Representative Henry D. Flood also brought up statistics relating to injuries and deaths that occurred during a train wreck and other railroad accidents.
1892: Buffalo switchmen's strike.
1894: Pullman Strike.
1901: Brotherhood of Railroad Signalmen.
1903: Elkins Act.
1906: Hepburn Act.
1908: Federal Employers Liability Act.
Railway Rate Act of 1910.
1913: Valuation Act.
1916: Adamson Act.
1917 - 1920: United States Railroad Administration.
Great Railroad Strike of 1922.
1926: Railroad Labor Act.
1934: RLA Amendments
Motor Carrier Act of 1935
1936: RLA Amendments.
1971: Amtrak.
1974 - 1986: United States Railway Association.
1976: Railroad Revitalization and Regulatory Reform Act.
1980: Staggers Rail Act.
Motor Carrier Act of 1980.
1996: Surface Transportation Board.
